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However, far less attention has focused on the durability of GI tolerability and persistence after extended exposure

[1] [2] 25 mg Speed of titration : Patients who increase their dose too rapidly or skip the recommended titration schedule experience more severe symptoms Individual susceptibility : Some patients are more prone to gastrointestinal side effects due to pre-existing conditions such as gastroparesis or functional dyspepsia Dietary habits : Consuming large, high-fat meals whilst on Ozempic can exacerbate nausea and vomiting Most patients who experience vomiting find that symptoms are most troublesome during the first 4-8 weeks of treatment or following dose escalation

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Think of it like adding more cars to an already congested highway